| 0:00 GMT |
8:00 GMT |
16:00 GMT |
WELCOME |
| Welcome to 2nd Annual World Coma Day Event |
Olivia Gosseries (Belgium)
Keri S. Kim (USA) |
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| Updates in Curing Coma Campaign |
Claude Hemphill (USA)
DaiWai Olson (USA) |
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| 0:20 GMT |
8:20 GMT |
16:20 GMT |
TOPIC 1: Introduction to Coma (35 minutes) |
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This session serves as an introduction to the history of coma and the different clinical entities after a severe brain injury. It will provide the story of a post-coma patient who recovered well and provides background on how providers assess patients in the ICU.
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Patient Story: Miracle of Life
Kertisha was a patient with anti-NMDA encephalitis who woke up from coma after 7 months and is now living a completely normal life as a dental assistant. This interview talks briefly about her condition, her recovery process and her life as a coma survivor.
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Kertisha Branson (USA)
Shraddha Mainali (USA) |
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| Education: Clinical assessment of coma in acute setting |
Shraddha Mainali (USA) |
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| Research: Historical perspective and definition of coma and disorders of consciousness (DoC) |
Eelco Wijdicks (USA)
Stephan Mayer (USA) |
| 0:55 GMT |
8:55 GMT |
16:55 GMT |
TOPIC 2: Dream Team (35 minutes) |
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Who are all of the people involved in the journey of coma patients? This session will provide a description of the various members of the professional/medical team and what they do, as well as give an overview of the path of recovery in different countries.
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Provider Story: Who are you? Who am I?/Education: Multi-disciplinary team approach
The NCS Trainee Section highlights the various members of the team involved in caring for patients in a coma. These cases are medically complex and require specialized care in managing and supporting their bodies as they recover from coma.
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Shweta Goswami (USA) |
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| Research: Path to recovery of consciousness in different countries |
Willemijn Erp (Netherlands)
Haibo Di (China)
Ekatherina Kondratyeva (Russia)
Suparna Gangopadhyay (India) |
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| 1:30 GMT |
9:30 GMT |
17:30 GMT |
TOPIC 3: Patient Advocacy (35 minutes) |
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In addition to the medical team, the patient needs strong support from their families, support groups and researchers. This session will feature a presentation from individuals in each of these areas who will provide their perspective on impact the challenges of dealing with coma.
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| Family Story: Struggles of family advocacy |
Patient’s mother
Varina Boerwinkle (USA)
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| Education: Support groups’ perspective on impact on public health and societal challenges |
Christine Buckley (USA)
Elchanan Schwarz (USA)
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| Researchers: Researchers’ perspective on impact on public health and societal challenges |
Steven Laureys (Belgium) |
| 2:05 GMT |
10:05 GMT |
18:05 GMT |
LIVE Discussion (20 minutes) |
| Live Discussion: Coma Care (Topics 1-3) |
- 02:05 GMT: Cassia Righy (Brazil)
Kent Owusu (USA)
- 10:05 GMT: Katja Wartenberg (Germany)
Rita Formisano (Italy)
- 18:05 GMT: Jeffrey J. Mucksavage (USA)
Risa Richardson (USA)
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Shout-out Videos (5 minutes)
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| 2:30 GMT |
10:30 GMT |
18:30 GMT |
TOPIC 4: Behavioral diagnosis (35 minutes) |
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This session will focus on the specifics of a behavioral diagnosis of coma and the questions and considerations. It will also feature the story of a patient who was misdiagnosed for a long time as he suffered from locked-in syndrome.
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Patient Story: Locked-in Syndrome (LIS)
Journey of Tars Peeters who was diagnosed late as locked-in syndrome. Story told my his mother, Nelleke Koeners.
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Nelleke Koeners (Belgium) |
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Education: What is considered as signs of consciousness?
This talk explains the disorders of consciousness, the behavioral signs indicating consciousness, and mentions new potential signs of consciousness.
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Anat Arzi (Israel) |
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| Research: Behavioral assessments in DoC and LIS |
Caroline Schnakers (USA) |
| 3:05 GMT |
11:05 GMT |
19:05 GMT |
TOPIC 5: Prognosis (35 minutes) |
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This session will focus on the prognosis and recovery of coma patients and how we manage them. It also features the case of a patient who was diagnosed as brain dead, but still lived for many years, as well as an assessment of the current factors that we can take into account to predict the outcome of a patient.
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| Patient Story: The Jahi McMath case |
Calixto Machado (Cuba) |
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Education: Prognosis of coma and DoC after acute brain injury
Patients in a vegetative state and with a nontraumatic etiology have a worse clinical outcome than patients in a minimally conscious state and with a traumatic etiology in terms of survival and clinical improvement, but late recovery of consciousness is possible in all diagnostic and etiologic groups. Although there are promising prognostic neurophysiologic markers that are easy to record at the patient's bedside, such as EEG reactivity, only a combined multimodal assessment could provide robust prognostic information to help clinicians and patients' families in the difficult decision-making process.
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Anna Estraneo (Italy) |
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Research: Hope for the future: genomic and biomarkers of recovery in DoC
This presentation highlights a few promising biomarkers of disorders of consciousness and challenges to the field.
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Sheila Alexander (USA) |
| 3:40 GMT |
11:40 GMT |
19:40 GMT |
TOPIC 6: Brain Imaging in Coma (35 minutes) |
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This session will cover the basics of how we use brain imaging to improve diagnosis and prognosis of coma & DoC patients. It also features the case of a patient who underwent a multimodal evaluation using brain imaging with good results while unresponsive at the bedside and who subsequently recovered, as well as an explanation on how we can use electroencephalography in the ICU to better document the state of the patient.
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Patient Story: Multimodal assessments followed by positive outcome
A patient story highlighting the possible delayed recovery following a severe brain injury and the importance of multimodal brain-imaging to anticipate this positive outcome.
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Bertrand Hermann (France) |
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Education: Electrophysiology in acute settings
Acute care of patients with coma following brain injury is complex, but brain monitoring with electroencephalography (EEG) can help guide clinicians on seizure management, sedation titration, as well evaluation potential for coma recovery. Novel paradigms and algorithms for patient stimulation and decoding of higher order processes using EEG may advance the assessment of consciousness and give voice to patients who may otherwise be unable to communicate. This presentation will provide an overview of EEG monitoring practice in acute settings with a focus on coma recovery evaluation.
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Edilberto Amorim (USA/Brazil) |
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Research: Transcranial magnetic stimulation and EEG in DoC
By combining TMS direct cortical perturbations with EEG recordings allows assessing the brain's internal capacity to sustain complex patterns of interactions, independently of sensory processing and motor behavior, the resulting index (called the perturbational complexity index, PCI) provides an accurate stratification of DoC patients as well as novel insight on the cortical mechanisms of loss and recovery of consciousness.
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Marcello Massimini (Italy) |
| 4:15 GMT |
12:15 GMT |
20:15 GMT |
LIVE Discussion (20 minutes) |
| Live Discussion: diagnosis, prognosis, brain imaging (Topics 4-6) |
- 04:15 GMT: Vigneswaran Veeramuthu (Malaysia)
- 12:15 GMT: Marek Binder (Poland)
Kasia Kasica (Poland)
- 20:15 GMT: Melanie Boly (USA)
Joe Giacino (USA)
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| Shout-out Videos (5 minutes) |
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| 4:40 GMT |
12:40 GMT |
20:40 GMT |
TOPIC 7: Treatment (35 minutes)
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This session will provide an overview of the different ways we can try to improve recovery. It also features the case of a patient who paradoxically responded to Zolpidem (he "wakes up" when he takes zolpidem/ambien/stilnox, but just for the time of the medication, after goes back to previous state) and what we learned from that case.
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| Patient Story: A case of zolpidem paradoxical responder |
Nicholas Schiff (USA) |
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| Education: Neurostimulant drug therapy in DoC |
Paola Saccucci (Canada) |
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| Research: Brain stimulation therapy |
Xuehai Wu (China)
Guoyi Gao/Junfeng Feng (China)
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| 5:15 GMT |
13:15 GMT |
21:15 GMT |
TOPIC 8: Rehabilitation (35 minutes)
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This session features an overview of what happens during the rehabilitation phase after a patient is released from the ICU, as well as a patient story about their rehabilitation and an overview of ongoing research related to rehabilitation.
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| Patient Story: Brain Path |
Janet Sutherland (USA) |
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| Education: What should you know about rehabilitation in DoC |
Brooke Murtaugh (USA)
Jayanthi Srinath (USA)
Neha Dangayach (USA)
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| Research: Research in rehabilitation |
Madhusree Sengupta (India)
Sucheta Saha (India)
Abhirupa Chakraborty (India)
Sachin Pradhan (India)
Dawa Tshering Lepeha (India)
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| 5:50 GMT |
13:50 GMT |
21:50 GMT |
TOPIC 9: Coma Memories (35 minutes) |
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This session discusses the memories patients experience of coma and near death experience. You will hear from the testimony of a patient who had a near-death experience (NDE) while in a coma due to a meningitis as well as an overview of the basic explanations of NDE and hypothesis of the origin of these particular phenomena.
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| Patient Story: Testimony of a near-death experience during coma |
Chris Pelton (UK) |
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Education: Fact or fiction: memories of coma
Following a coma, people may report some extraordinary memories, such as episodes of near-death experiences. Charlotte Martial gives a brief overview of the current literature on near-death experiences.
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Charlotte Martial (Belgium) |
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| Research: Evolutionary origin of near-death experiences |
Daniel Kondziella (Denmark) |
| 6:25 GMT |
14:25 GMT |
22:25 GMT |
LIVE Discussion (20 minutes) |
| Live Discussion: Treatment, Rehabilitation and Coma Memories (Topics 7-9) |
- 06:25 GMT: Geraldine Mariano (Philippines)
Stephanie D'Souza (Australia)
- 14:25 GMT: Enrique Noe (Spain)
Karin Diseren (Switzerland)
- 22:25 GMT: Rennan M. Ribeiro (Brazil)
Gisele Silva (Brazil)
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| Shout-out Videos (5 minutes) |
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| 6:50 GMT |
14:50 GMT |
22:50 GMT |
TOPIC 10: Pediatric (35 minutes) |
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This session focuses specifically on pediatric patients and what we know about children who have had a severe brain injury. It also features the story of one family’s experience, as well as a presentation on the state of the art review on diagnosis, prognosis and therapy in the pediatric population of DoC.
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Patient Story: Road to recovery of consciousness
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Elijah “Eli” Sanchez (USA)
Victor Sanchez (USA)
Jannette Dodge (USA)
Varina Boerwinkle (USA) |
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Education/Research: DoC research in pediatrics
In this talk, Dr. Beth Slomine reviews the methodology and preliminary results of the a pediatric scoping review that is being conducted by the International Brain Injury Association’s Disorders of Consciousness Special Interest Group. The aim of the project is to review the world’s literature on diagnosis, outcome/prognosis, and treatment of pediatric disorders of consciousness.
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Beth Slomine (USA) |
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| 7:25 GMT |
15:25 GMT |
23:25 GMT |
TOPIC 11: Ethics in coma and DoC (15 minutes) |
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This session will discuss various ethical issues and challenges around the theme of coma and disorders of consciousness.
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Education: Ethical considerations in coma and DoC
Disorders of consciousness (DOCs) raise several ethical issues. For the sake of analysis, they can be divided in foundational and practical issues. Foundational issues have to do with how we conceive concepts that play a fundamental role in our ethical analysis, for instance consciousness and its ethical relevance. Practical issues have to do with how we handle a number of challenges like the need for improving the diagnosis of DOCs and the detection of patients' needs.
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Michele Farisco (Sweden) |
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| 7:40 GMT |
15:40 GMT |
23:40 GMT |
LIVE Discussion (20 minutes) |
| Live Discussion: Pediatrics and Ethics (Topics 10-11) |
- 07:40 GMT: Sally Rothemeyer (South Africa)
Stephanie D'Souza (Australia)
- 15:40 GMT: Kathinka Evers (Sweden)
Erika Molteni (UK)
- 23:40 GMT: Varina Boerwinkle (USA)
Matt Kirschten (USA)
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Closing remarks |
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